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Interaction with other medicines

During the treatment of severe depressive disorders, doctors prescribe combination therapy using several antidepressants at once..

Important! The combination of such drugs as Mirtazapine and Bupropion demonstrates the greatest efficiency - it is precisely such a combination that doctors prefer for hypersomnia, motor inhibition. https://perfecthealthus.com/buy-mirtazapine-15mg-30mg-online/ Studies have shown that combining these drugs doubles the incidence of long-term, stable remissions..

Mirtazapine may also be combined with medicines such as fluoxetine or venlafaxine..

Mirtazapine may contribute to:

 

  1. Strengthening the sedative effects of drugs, benzodiazepine derivatives, as well as other medications with a sedative effect. It is recommended to refrain from such a combination of drugs..
  2. Hypertensive crisis. When combined with clonidine-based drugs.
  3. Severe psychoses. When combined with drugs, which include levodopa.
  4. Hypomania. When combined with sertraline.
  5. Inhibition of the central nervous system, if you combine the medicine with alcohol.

 

You should refrain from using Mirtazapine at the same time, as well as 14 days after the withdrawal of MAO inhibitors.

Special instructions for the use of the drug Mirtazapine

The results of experimental studies indicate the absence of a teratogenic effect, however, clinical data on the effectiveness and safety of mirtazapine during pregnancy and lactation are not available. Caution is prescribed in patients with epilepsy and organic brain damage, with impaired liver and / or kidney function, in patients with angina pectoris. and / or recent myocardial infarction, with impaired cardiac conduction, with arterial hypotension, with impaired urination with hypertrophy of the prostate gland, patients with acute angle-closure glaucoma and increased intraocular pressure, with diabetes. When using mirtazapine in patients with schizophrenia or other psychotic disorders, psychotic symptoms and delusional experiences may intensify. In the treatment of the depressive phase of biopolar affective disorders, this condition can go into the phase of mania. It should be borne in mind that with the development of symptoms such as fever, sore throat, stomatitis during treatment with mirtazapine, discontinue treatment immediately. may lead to nausea, headache and a general deterioration in well-being. During treatment with mirtazapine, you should refrain from drinking alcohol. Mirtazapine should be prescribed with caution to patients taking potentially dangerous activities requiring increased attention and speed of psychomotor reactions (including driving).

Adverse reactions

  • Inhibition, distraction, drowsiness
  • Migraine, headaches, dizziness
  • Tremor of limbs, cramps
  • Indifference and apathy
  • Hostility, anger, manic state
  • Inhibition of hematopoietic function (changes in blood tests)
  • Increased appetite, weight gain
  • Heart rhythm disorders
  • Dyspeptic disorders
  • Gingivitis, stomatitis.

Such reactions also occur in the first few weeks of treatment with the drug, usually they decrease or disappear completely by 3-4 weeks.

Purchase of medicines and analogues

Mirtazapine is available in tablets, and their price is 1,500 rubles..

Keep the medicine in a dry place, protected from the sun. Permissible storage temperature is from +2 to +30 degrees Celsius. You also need to keep this medication away from children's eyes and hands..

Prescription drug is available only with a prescription.

This drug has no analogues on the active substance, since Mirtazapine has a unique and unique composition. However, in terms of their overall effect, there are similar means:

 

  • Alventa - suppression of a depressive state;
  • Velaxin - treatment of protracted episodes of depression;
  • Venlaxor - prevention of depression and its manifestations;
  • and numerous other antidepressants (complete list of the best).

 

pharmachologic effect

The drug enhances central noradrenergic and serotonergic transmission. http://en.m.wikipedia.org/wiki/Mirtazapine Due to the main active ingredient, mirtazapine, we can talk about blocking histamine receptors and a pronounced sedative effect.

Therapeutic doses of an antidepressant do not adversely affect the functioning of the cardiovascular system. Clinical studies have confirmed sleeping pills. Due to the sedative effect, the drug is not addictive, and does not increase the suicidal mood.